Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology, Ballygunge Science College, 4th Floor, University of Calcutta.35, Ballygunge Circular Road, Kolkata- 700 019, West Bengal, India.
Aminoacyl-tRNA synthetases from plants, must come to terms not only with discriminating between the 20 common amino acids but must also contend with related potentially toxic analogues. L-canavanine has been found to occur as a toxic nonprotein amino acid in more than 1500 leguminous plants. One mechanism of its toxicity is its incorporation into proteins, replacing arginine and giving rise to...